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Mutation Information
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Mutation Site
|
K169E |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
Env |
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Country
|
South Africa |
Literature Information
|
PubMed PMID
|
29950423
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2018 |
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Journal
|
Journal of virology |
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Title
|
HIV-1 Subtype C-Infected Children with Exceptional Neutralization Breadth Exhibit Polyclonal Responses Targeting Known Epitopes. |
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Author
|
Ditse Z,Muenchhoff M,Adland E,Jooste P,Goulder P,Moore PL,Morris L |
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Evidence
|
For V2-glycan antibodies, we used both N160A/K and K169E mutants, as some V2-directed antibodies, such as the CAP256-VRC26 lineage, exhibit limited glycan dependence.
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HIV Mutation Detail Information