Mutation Information
Mutation Site
|
K160T |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
IN |
Literature Information
PubMed PMID
|
18687142
|
Published Year
|
2008 |
Journal
|
Retrovirology |
Title
|
Natural variation of HIV-1 group M integrase: implications for a new class of antiretroviral inhibitors. |
Author
|
Rhee SY,Liu TF,Kiuchi M,Zioni R,Gifford RJ,Holmes SP,Shafer RW |
Evidence
|
E157Q, which decreases raltegravir and elvitegravir susceptibility, was associated with K160Q/T in subtypes A, B, C, and CRF02 and with K156N in three unrelated subtype D isolates.
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