Mutation Information
Mutation Site
|
K14E |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
PR |
Literature Information
PubMed PMID
|
31622432
|
Published Year
|
2019 |
Journal
|
PloS one |
Title
|
Resistance profile of the HIV-1 maturation inhibitor GSK3532795 in vitro and in a clinical study. |
Author
|
Dicker I,Zhang S,Ray N,Beno BR,Regueiro-Ren A,Joshi S,Cockett M,Krystal M,Lataillade M |
Evidence
|
In the passages initiated with culture-adapted (p12) V370A-containing virus, a different pattern of substitutions was seen, with V362I dominating at passage 8 in both cultures, in one case accompanied by K114V in the MA and K14E in Pr, and in the other case by N235T (present at 50%) (Table 2).
|
|
|