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Mutation Information
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Mutation Site
|
K141I |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
S |
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Immune Escape
|
Y |
Literature Information
|
PubMed PMID
|
32790777
|
|
Published Year
|
2020 |
|
Journal
|
PloS one |
|
Title
|
A recombinant human immunoglobulin with coherent avidity to hepatitis B virus surface antigens of various viral genotypes and clinical mutants. |
|
Author
|
Jeong GU,Ahn BY,Jung J,Kim H,Kim TH,Kim W,Lee A,Lee K,Kim JH |
|
Evidence
|
In contrast, the polyclonal anti-HBsAg antibody signal was severely reduced in several mutants within the 2nd loop of ‘a’ determinant, such as K141I, P142L/S, D144A/E, G145K/R, N146S and T148I.
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HBV Mutation Detail Information