|
Mutation Information
|
Mutation Site
|
K141E |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
C |
|
Viral Reference
|
AB033557
|
|
Country
|
China |
Literature Information
|
PubMed PMID
|
23254298
|
|
Disease
|
HBV infection
|
|
Published Year
|
2013 |
|
Journal
|
Clinical and vaccine immunology : CVI |
|
Title
|
Hepatitis B virus surface antigen (HBsAg)-positive and HBsAg-negative hepatitis B virus infection among mother-teenager pairs 13 years after neonatal hepatitis B virus vaccination. |
|
Author
|
Yao QQ,Dong XL,Wang XC,Ge SX,Hu AQ,Liu HY,Wang YA,Yuan Q,Zheng YJ |
|
Evidence
|
In comparison with the (hp)HBI cases, those with (hn)HBI had a lower level of HBV load and a higher proportion of genotype-C strains, which were accompanied by differentiated mutations (Q129R, K141E, and Y161N) of the "a" determinant of the HBV surface gene.
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|
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HBV Mutation Detail Information