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Mutation Information
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Mutation Site
|
K12N |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
Tat |
Literature Information
|
PubMed PMID
|
30824746
|
|
Published Year
|
2019 |
|
Journal
|
Scientific reports |
|
Title
|
A Naturally Occurring Polymorphism in the HIV-1 Tat Basic Domain Inhibits Uptake by Bystander Cells and Leads to Reduced Neuroinflammation. |
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Author
|
Ruiz AP,Ajasin DO,Ramasamy S,DesMarais V,Eugenin EA,Prasad VR |
|
Evidence
|
In order to ensure equivalent detection of all Tat proteins, we introduced mutations in Tat-B expression constructs to create amino acid substitutions R7N and K12N of both the wild type and R57S variants.
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HIV Mutation Detail Information