|
Mutation Information
|
Mutation Site
|
K122R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
A |
|
Immune Escape
|
Y |
|
Country
|
South Africa |
Literature Information
|
PubMed PMID
|
30377627
|
|
Disease
|
HBV infection
|
|
Published Year
|
2018 |
|
Journal
|
Open forum infectious diseases |
|
Title
|
Hepatitis B Virus (HBV) Infection and Re-activation During Nucleos(t)ide Reverse Transcriptase Inhibitor-Sparing Antiretroviral Therapy in a High-HBV Endemicity Setting. |
|
Author
|
Abdullahi A,Fopoussi OM,Torimiro J,Atkins M,Kouanfack C,Geretti AM |
|
Evidence
|
In one case of reactivation, anti-HBs increased from 14 to >1000 IU/L; sequencing showed HBV genotype A3 and 3 escape mutations in surface (Y100C, K122R, Y161FY).
|
|
|
HBV Mutation Detail Information