HIV Mutation Detail Information

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Mutation Information

Mutation Site	K122E
Mutation Type	Amino acid level
Gene/Protein/Region Type	PR
Relevant Drug	NRTIs;NNRTIs

Literature Information

PubMed PMID	32053707
Published Year	2020
Journal	PLoS pathogens
Title	HIV protease cleaves the antiviral m6A reader protein YTHDF3 in the viral particle.
Author	Jurczyszak D,Zhang W,Terry SN,Kehrer T,Bermúdez González MC,McGregor E,Mulder LCF,Eckwahl MJ,Pan T,Simon V
Evidence	NL4-3-Δenv-eGFP MDR1 and MDR2 encode the following drug resistance associated mutations (MDR1 Protease: L10V, I13V, G16A, K20R, E35D, M36I, R41K, I64V, H69K, A71V, I84V, L90M, I93M;MDR1 RT: E6K, V35K, M41L, K49R, I50V, L74V, L100I, K103N, K122E, D123E, I135L;MDR2 Protease: I13V, I64V, V77I, L90M;MDR2 RT: M41L, K43E, S68G, V106A, K122E, D123E, I135T, see also Table 1).

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation