EBV Mutation Detail Information

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Mutation Information

Mutation Site	K122A
Mutation Type	Amino acid level
Gene/Protein/Region Type	BILF1

Literature Information

PubMed PMID	19119421
Published Year	2009
Journal	PLoS pathogens
Title	The Epstein-Barr virus G-protein-coupled receptor contributes to immune evasion by targeting MHC class I molecules for degradation.
Author	Zuo J,Currin A,Griffin BD,Shannon-Lowe C,Thomas WA,Ressing ME,Wiertz EJ,Rowe M
Evidence	Substitution of an alanine for lysine at residue 122 abolished G-protein activation and BILF1 signaling function, as we observed by transfecting wild-type BILF1 or the K122A-BILF1 mutant into the HEK293-NFkappaB reporter line.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation