HIV Mutation Detail Information

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Mutation Information

Mutation Site	K114V
Mutation Type	Amino acid level
Gene/Protein/Region Type	Gag

Literature Information

PubMed PMID	31622432
Published Year	2019
Journal	PloS one
Title	Resistance profile of the HIV-1 maturation inhibitor GSK3532795 in vitro and in a clinical study.
Author	Dicker I,Zhang S,Ray N,Beno BR,Regueiro-Ren A,Joshi S,Cockett M,Krystal M,Lataillade M
Evidence	In the passages initiated with culture-adapted (p12) V370A-containing virus, a different pattern of substitutions was seen, with V362I dominating at passage 8 in both cultures, in one case accompanied by K114V in the MA and K14E in Pr, and in the other case by N235T (present at 50%) (Table 2).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation