HIV Mutation Detail Information

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Mutation Information
Mutation Site K103S
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug NRTIs
Country Uganda
Literature Information
PubMed PMID 32025714
Disease HIV infection/AIDS
Published Year 2020
Journal The Journal of antimicrobial chemotherapy
Title Prevalence of viral load suppression, predictors of virological failure and patterns of HIV drug resistance after 12 and 48 months on first-line antiretroviral therapy: a national cross-sectional survey in Uganda.
Author Ssemwanga D,Asio J,Watera C,Nannyonjo M,Nassolo F,Lunkuse S,Salazar-Gonzalez JF,Salazar MG,Sanyu G,Lutalo T,Kabuga U,Ssewanyana I,Namatovu F,Namayanja G,Namale A,Raizes E,Kaggwa M,Namuwenge N,Kirungi W,Katongole-Mbidde E,Kaleebu P,Uganda HIV Drug Resistance Technical Working Group.
Evidence Of the 28 patients with mutations, 82.1% had M184V/I, 75% had K103N/S, 28.6% had K65R mutations, 32% had thymidine analogue mutations (TAMs) and 64.3% of participants had the M184V/I NRTI mutation.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation