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Mutation Information
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Mutation Site
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K103S |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
RT |
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Genotype/Subtype
|
B |
|
Country
|
Canada;US |
Literature Information
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PubMed PMID
|
18666824
|
|
Disease
|
HIV infection/AIDS
|
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Published Year
|
2008 |
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Journal
|
PLoS medicine |
|
Title
|
Minority HIV-1 drug resistance mutations are present in antiretroviral treatment-naïve populations and associate with reduced treatment efficacy. |
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Author
|
Johnson JA,Li JF,Wei X,Lipscomb J,Irlbeck D,Craig C,Smith A,Bennett DE,Monsour M,Sandstrom P,Lanier ER,Heneine W |
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Evidence
|
The remaining resistance mutation assays identified eight (4%) K103N, seven (3.5%) L90M, three (1.5%) Y181C, two (1.5%) M184V, one (0.5%) T215Y, and four (2%) T215F samples. Four samples (2% overall) had the following mutations to two drug classes: L90M+M184V, L90M+Y181C, Y181C+T215F, and L90M+M41L+K70R.
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HIV Mutation Detail Information