|
Mutation Information
|
Mutation Site
|
K103R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
rilpivirine (RPV);etravirine (ETR) |
|
Country
|
USA |
Literature Information
|
PubMed PMID
|
32371875
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
Scientific reports |
|
Title
|
HIV-1 molecular epidemiology and drug resistance-associated mutations among treatment-naïve blood donors in China. |
|
Author
|
Zhao J,Lv X,Chang L,Ji H,Harris BJ,Zhang L,Jiang X,Guo F,Hackett J Jr,Yin P,Cloherty GA,Rodgers MA,Wang L |
|
Evidence
|
The combination of V179D and K103R defined as NNRTI DRM act synergistically to reduce EFV and NVP susceptibility.
|
|
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HIV Mutation Detail Information