Mutation Information
Mutation Site
|
K103R |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Genotype/Subtype
|
A;B;C;AE |
Country
|
Belgium;Cameroon;China;Honduras;India;South Africa;Thailand |
Literature Information
PubMed PMID
|
18614915
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2008 |
Journal
|
Journal of acquired immune deficiency syndromes (1999) |
Title
|
Optimization of the oligonucleotide ligation assay, a rapid and inexpensive test for detection of HIV-1 drug resistance mutations, for non-North American variants. |
Author
|
Beck IA,Crowell C,Kittoe R,Bredell H,Machaba M,Willamson C,Janssens W,Jallow S,van der Groen G,Shao Y,Jacob M,Samuel NM,de Rivera IL,Ngo-Giang-Huong N,Cassol S,Alemnji G,Frenkel LM |
Evidence
|
Also of interest, a polymorphism 2 bases from the ligation site of RT codon 103 (AAA AGA) encoded a K103R mutation that has not been associated with resistance (Table 3) and was observed only in subtype B specimens from Honduras.
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