HIV Mutation Detail Information

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Mutation Information
Mutation Site K103N
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Genotype/Subtype C
Relevant Drug NNRTIs
Country South Africa
Literature Information
PubMed PMID 33632139
Disease HIV infection/AIDS
Published Year 2021
Journal BMC infectious diseases
Title Increased acquired protease inhibitor drug resistance mutations in minor HIV-1 quasispecies from infected patients suspected of failing on national second-line therapy in South Africa.
Author Obasa AE,Ambikan AT,Gupta S,Neogi U,Jacobs GB
Evidence The majority of the drug resistance mutations in the minor viral quasispecies were observed in the V82A mutation (n = 13) in protease and K65R (n = 5), K103N (n = 7) and M184V (n = 5) in reverse transcriptase.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation