|
Mutation Information
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Mutation Site
|
K103N |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
efavirenz (EFV);nevirapine (NVP) |
|
Country
|
Indian |
Literature Information
|
PubMed PMID
|
33390085
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2021 |
|
Journal
|
AIDS research and human retroviruses |
|
Title
|
Detection of Drug Resistance Mutations in the Reverse Transcriptase Gene of HIV-1-Infected North Indian Population Failing First-Line Antiretroviral Therapy "A Follow-Up Cohort Study". |
|
Author
|
Barik SK,Bansal AK,Mohanty PS,Tripathy SP,Hanna LE,Karunaianantham R,Pattabiraman S,Singh TP,Tandon R,Tomar S,Jena S,Patil SA,Mohanty KK |
|
Evidence
|
Drug resistance mutation M184V (ATG to GTA) (63.15%) associated with lamivudine and abacavir and K103N (AAG or AAA to AAU) (36.84%) associated with efavirenz and nevirapine were predominantly identified in first line ART failure patients.
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HIV Mutation Detail Information