HIV Mutation Detail Information

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Mutation Information
Mutation Site K103N
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Genotype/Subtype CRF07_BC; CRF08_BC; CRF01_AE; B; CRF55_01B; CRF59_01B;CRF68_01B
Relevant Drug NNRTIs
Country China
Literature Information
PubMed PMID 33347449
Disease HIV infection/AIDS
Published Year 2020
Journal PloS one
Title The genotype distribution, infection stage and drug resistance mutation profile of human immunodeficiency virus-1 among the infected blood donors from five Chinese blood centers, 2014-2017.
Author Liang S,Liu Z,Wang S,Liu J,Shi L,Mao W,Liu C,Wan J,Zhu L,Huang M,Liu Y,Wang J,Ness P,Shan H,Zeng P,He M
Evidence 48 DRMs were identified from 43 samples, indicating a drug resistance prevalence of 12.1% (43/356), which include seven protease inhibitors (PIs) accessory DRMs (Q58E, L23I and I84M), two PIs major DRMs (M46I, M46L), seven nucleoside RT inhibitors DRMs (D67N, K70Q, K219R and M184L), and 32 non-nucleoside RT inhibitors DRMs (K103N, V179E, K238N, V179D, E138G, G190E, A98G, Y188D and E138A).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation