Mutation Information
Mutation Site
|
K103N |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
rilpivirine (RPV);NNRTIs;NRTIs;PIs |
Country
|
Portuguese |
Literature Information
PubMed PMID
|
33143301
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2020 |
Journal
|
Viruses |
Title
|
Increasing Prevalence of HIV-1 Transmitted Drug Resistance in Portugal: Implications for First Line Treatment Recommendations. |
Author
|
Pingarilho M,Pimentel V,Diogo I,Fernandes S,Miranda M,Pineda-Pena A,Libin P,Theys K,Martins MRO,Vandamme AM,Camacho R,Gomes P,Abecasis A |
Evidence
|
The most frequently detected mutations were K103NS (3.2%) conferring resistance to NNRTIs, followed by M41L (1.6%) and M184V/I mutations (1.3%) conferring resistance to NRTIs, and L90M (1.2%) conferring resistance to PIs (Figure 2A).
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