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Mutation Information
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Mutation Site
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K103N |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
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Genotype/Subtype
|
CRF10_CD;A1;C;D |
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Relevant Drug
|
zidovudine (AZT);lamivudine (LAM);efavirenz (EFV);tenofovir (TDF);abacavir (ABC);lopinavir (LPV);zidovudine (ZVD);nevirapine (NPV);emtricitabine (FTC) |
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Country
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Northern Tanzania |
Literature Information
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PubMed PMID
|
32986709
|
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Disease
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HIV infection/AIDS
|
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Published Year
|
2020 |
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Journal
|
PloS one |
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Title
|
Patterns of acquired HIV-1 drug resistance mutations and predictors of virological failure in Moshi, Northern Tanzania. |
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Author
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Mziray SR,Kumburu HH,Assey HB,Sonda TB,Mahande MJ,Msuya SE,Kiwelu IE |
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Evidence
|
Frequent NNRTI-resistance associated mutations were K103N (n = 11), V106M (n = 5) and G190A (n = 5). Prevalent nucleoside analogue reverse transcriptase inhibitors-resistance associated mutations were M184V (n = 17), K70R (n = 7) and D67N (n = 6).
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HIV Mutation Detail Information