|
Mutation Information
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Mutation Site
|
K103N |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.Y101C+rt.K103N |
|
Relevant Drug
|
nevirapine (NPV);efavirenz (EFV) |
Literature Information
|
PubMed PMID
|
32394235
|
|
Published Year
|
2021 |
|
Journal
|
Molecular diversity |
|
Title
|
Synthetic strategies, SAR studies, and computer modeling of indole 2 and 3-carboxamides as the strong enzyme inhibitors: a review. |
|
Author
|
Chehardoli G,Bahmani A |
|
Evidence
|
The important point about double mutant K103N-Y101C is that molecule 25 has higher activity than molecules 22 and 24.
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|
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HIV Mutation Detail Information