|
Mutation Information
|
Mutation Site
|
K103N |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
efavirenz (EFV);nevirapine (NVP) |
|
Country
|
USA |
Literature Information
|
PubMed PMID
|
32371875
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
Scientific reports |
|
Title
|
HIV-1 molecular epidemiology and drug resistance-associated mutations among treatment-naïve blood donors in China. |
|
Author
|
Zhao J,Lv X,Chang L,Ji H,Harris BJ,Zhang L,Jiang X,Guo F,Hackett J Jr,Yin P,Cloherty GA,Rodgers MA,Wang L |
|
Evidence
|
Furthermore, 4 HIV-1 isolates (2.4%, 4/168) had surveillance drug-resistance mutation (SDRM), including 3 nonnucleosidereverse transcriptase inhibitors (NNRTI) SDRMs (1 K101E, 2 K103N) and 1 protease inhibitor (PI) SDRM (M46I).
|
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HIV Mutation Detail Information