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Mutation Information
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Mutation Site
|
K103N |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Viral Reference
|
K03455.1
|
|
Relevant Drug
|
NNRTIs |
|
Country
|
Iran |
Literature Information
|
PubMed PMID
|
32360523
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
Microbial pathogenesis |
|
Title
|
HIV-1 drug resistance mutations detection and HIV-1 subtype G report by using next-generation sequencing platform. |
|
Author
|
Gholami M,Rouzbahani N,Samiee S,Tayeri K,Ghorban K,Dehkharghani AD,Gholami AA,Moshiri F,Sattari A,Dadmanesh M,Mohraz M |
|
Evidence
|
NRTI and NNRTI associated dominant mutations were M184I/V and K103 N.High-level resistance to lamivudine (3 TC) and Emtricitabine (FTC) were detected in 34.3% of patients while 53.1% were resistant to Efavirenz (EFV) and Nevirapine (NVP).
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HIV Mutation Detail Information