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Mutation Information
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Mutation Site
|
K103N |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
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Relevant Drug
|
NRTIs |
|
Country
|
Uganda |
Literature Information
|
PubMed PMID
|
32025714
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
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Journal
|
The Journal of antimicrobial chemotherapy |
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Title
|
Prevalence of viral load suppression, predictors of virological failure and patterns of HIV drug resistance after 12 and 48 months on first-line antiretroviral therapy: a national cross-sectional survey in Uganda. |
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Author
|
Ssemwanga D,Asio J,Watera C,Nannyonjo M,Nassolo F,Lunkuse S,Salazar-Gonzalez JF,Salazar MG,Sanyu G,Lutalo T,Kabuga U,Ssewanyana I,Namatovu F,Namayanja G,Namale A,Raizes E,Kaggwa M,Namuwenge N,Kirungi W,Katongole-Mbidde E,Kaleebu P,Uganda HIV Drug Resistance Technical Working Group. |
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Evidence
|
Of the 28 patients with mutations, 82.1% had M184V/I, 75% had K103N/S, 28.6% had K65R mutations, 32% had thymidine analogue mutations (TAMs) and 64.3% of participants had the M184V/I NRTI mutation.
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HIV Mutation Detail Information