Mutation Information
Mutation Site
|
K103N |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
NNRTIs |
Literature Information
PubMed PMID
|
31242909
|
Published Year
|
2019 |
Journal
|
Retrovirology |
Title
|
NNRTI-induced HIV-1 protease-mediated cytotoxicity induces rapid death of CD4 T cells during productive infection and latency reversal. |
Author
|
Trinité B,Zhang H,Levy DN |
Evidence
|
We therefore compared the effect of the well described RT mutation K103N on both reverse-transcription inhibition and NNRTI-induced killing.
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