HIV Mutation Detail Information

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Mutation Information
Mutation Site K103N
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug NNRTIs
Country South Africa
Literature Information
PubMed PMID 31143879
Disease HIV infection/AIDS
Published Year 2019
Journal EClinicalMedicine
Title Trends in Pretreatment HIV-1 Drug Resistance in Antiretroviral Therapy-naive Adults in South Africa, 2000-2016: A Pooled Sequence Analysis.
Author Chimukangara B,Lessells RJ,Rhee SY,Giandhari J,Kharsany ABM,Naidoo K,Lewis L,Cawood C,Khanyile D,Ayalew KA,Diallo K,Samuel R,Hunt G,Vandormael A,Stray-Pedersen B,Gordon M,Makadzange T,Kiepiela P,Ramjee G,Ledwaba J,Kalimashe M,Morris L,Parikh UM,Mellors JW,Shafer RW,Katzenstein D,Moodley P,Gupta RK,Pillay D,Abdool Karim SS,de Oliveira T
Evidence The most prevalent mutation was K103NS, occurring in 278 sequences (58.2% of sequences with any DRM;4.0% of all sequences) (Fig. 3).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation