|
Mutation Information
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Mutation Site
|
K103N |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
C |
|
Relevant Drug
|
efavirenz (EFV);nevirapine (NPV);etravirine(ETR);rilpivirine (RPV) |
|
Country
|
Malawi |
Literature Information
|
PubMed PMID
|
29977795
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2018 |
|
Journal
|
African journal of laboratory medicine |
|
Title
|
Detection of minority drug resistant mutations in Malawian HIV-1 subtype C-positive patients initiating and on first-line antiretroviral therapy. |
|
Author
|
Zhou Z,Tang K,Zhang G,Wadonda-Kabondo N,Moyo K,Rowe LA,DeVos JR,Wagar N,Zheng DP,Guo H,Nkengasong J,Frace M,Sammons S,Yang C |
|
Evidence
|
The most common non-nucleoside reverse transcriptase inhibitor (NNRTI) mutations were K103N (58.1%), Y181C (41.9%) and G190A (6.5%), and the most frequent nucleoside reverse transcriptase inhibitor (NRTI) mutation was M184V (61.3%).
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HIV Mutation Detail Information