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Mutation Information
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Mutation Site
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K103N |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
RT |
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Viral Reference
|
K03455.1
|
|
Relevant Drug
|
NNRTIs |
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Country
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Brazil |
Literature Information
|
PubMed PMID
|
29844604
|
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Disease
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HIV-HBV coinfection;
HIV-HCV coinfection
|
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Published Year
|
2018 |
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Journal
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Scientific reports |
|
Title
|
HIV Reverse Transcriptase and Protease Genes Variability Can Be a Biomarker Associated with HIV and Hepatitis B or C Coinfection. |
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Author
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Cantão NM,Fogaça de Almeida L,Rodrigo Wolf I,Oliveira Almeida R,Alves de Almeida Cruz A,Nunes C,Barbosa AN,Valente GT,de Moura Campos Pardini MI,Grotto RMT |
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Evidence
|
K103N was the NNRTI mutation most frequently found in co-infected patients (14.7%). The major mutations to PI were I54V (2.9%), V82A (11.7%), M46I (8.8%) and L90M (40.4%). On the other hand, the minor mutations to PI found were S37N (32.3%), I15V (26.5%) and M36I (23.5%).
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HIV Mutation Detail Information