HIV Mutation Detail Information

> K103N Search Result

Mutation Information

Mutation Site	K103N
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	efavirenz (EFV);nevirapine (NVP)
Country	Canada;America;Belgium;France;Germany;Italy;Poland;Russia;Spain;England

Literature Information

PubMed PMID	29683855
Disease	HIV infection/AIDS
Published Year	2018
Journal	AIDS (London, England)
Title	A week-48 randomized phase-3 trial of darunavir/cobicistat/emtricitabine/tenofovir alafenamide in treatment-naive HIV-1 patients.
Author	Eron JJ,Orkin C,Gallant J,Molina JM,Negredo E,Antinori A,Mills A,Reynes J,Van Landuyt E,Lathouwers E,Hufkens V,Jezorwski J,Vanveggel S,Opsomer M,AMBER study group.
Evidence	This patient harbored a K103N mutation at screening, indicating transmitted NNRTI (efavirenz and nevirapine) resistance.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation