HIV Mutation Detail Information

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Mutation Information

Mutation Site	K103N
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	NNRTIs
Country	America

Literature Information

PubMed PMID	28159573
Disease	HIV infection/AIDS
Published Year	2017
Journal	EBioMedicine
Title	Factors Associated With the Control of Viral Replication and Virologic Breakthrough in a Recently Infected HIV-1 Controller.
Author	Walker-Sperling VE,Pohlmeyer CW,Veenhuis RT,May M,Luna KA,Kirkpatrick AR,Laeyendecker O,Cox AL,Carrington M,Bailey JR,Arduino RC,Blankson JN
Evidence	Our patient did have the major NNRTI mutation K103N, and the major protease inhibitor mutation, V82L, but the replicative capacity of a chimeric virus containing AC1 RT and protease genes was 77% by the PhenoSense HIV Assay (Monogram Biosciences, South San Francisco, CA).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation