|
Mutation Information
|
Mutation Site
|
K103N |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.V108I+rt.K103N;rt.P225H+rt.Y181C+rt.K103N;rt.P225H+rt.K103N;rt.F227L+rt.G190A+rt.V106M+rt.K103N+rt.K101H;rt.G190A+rt.K103N+rt.K101H;rt.P225H+rt.G190A+rt.K103N;rt.G190A+rt.V106A+rt.K103N;rt.V106M+rt.K103N |
|
Relevant Drug
|
NNRTIs |
|
Country
|
South Africa |
Literature Information
|
PubMed PMID
|
21927716
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2011 |
|
Journal
|
Journal of AIDS & clinical research |
|
Title
|
Drug resistance patterns and virus re-suppression among HIV-1 subtype C infected patients receiving non-nucleoside reverse transcriptase inhibitors in South Africa. |
|
Author
|
El-Khatib Z,Delong AK,Katzenstein D,Ekstrom AM,Ledwaba J,Mohapi L,Laher F,Petzold M,Morris L,Kantor R |
|
Evidence
|
Of 25 viremic patients followed for a median of 8 months on a continued first-line regimen, 12 (48%) re-suppressed, six with K103N and three with M184V.
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|
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HIV Mutation Detail Information