Mutation Information
Mutation Site
|
K103N |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Genotype/Subtype
|
B |
Relevant Drug
|
lopinavir (LPV);ritonavir;zidovudine (AZT);lamivudine (LAM) |
Country
|
Switzerland |
Literature Information
PubMed PMID
|
21754996
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2011 |
Journal
|
PloS one |
Title
|
Reappearance of minority K103N HIV-1 variants after interruption of ART initiated during primary HIV-1 infection. |
Author
|
Metzner KJ,Leemann C,Di Giallonardo F,Grube C,Scherrer AU,Braun D,Kuster H,Weber R,Guenthard HF |
Evidence
|
Reappearance of Minority K103N HIV-1 Variants after Interruption of ART Initiated during Primary HIV-1 InfectionIn the Zurich Primary HIV infection study (ZPHI), minority drug-resistant HIV-1 variants were detected in some acutely HIV-1-infected patients prior to initiation of early antiretroviral therapy (ART).
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