|
Mutation Information
|
Mutation Site
|
K103N |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.Y181C+rt.K103N;rt.K103T+rt.K103N |
|
Relevant Drug
|
nevirapine (NVP) |
|
Country
|
Uganda |
Literature Information
|
PubMed PMID
|
18582198
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2008 |
|
Journal
|
The Journal of infectious diseases |
|
Title
|
Nevirapine resistance in women and infants after first versus repeated use of single-dose nevirapine for prevention of HIV-1 vertical transmission. |
|
Author
|
Flys TS,McConnell MS,Matovu F,Church JD,Bagenda D,Khaki L,Bakaki P,Thigpen MC,Eure C,Fowler MG,Eshleman SH |
|
Evidence
|
The proportion of women with resistance, the types of mutations detected, and the frequency and level of K103N were similar in the two groups of women at 6 weeks and 6 months post-partum.
|
|
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HIV Mutation Detail Information