HIV Mutation Detail Information

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Mutation Information

Mutation Site	K103N
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	NNRTIs
Country	European

Literature Information

PubMed PMID	18419497
Disease	HIV infection/AIDS
Published Year	2008
Journal	Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Title	Plasma drug concentrations and virologic evaluations after stopping treatment with nonnucleoside reverse-transcriptase inhibitors in HIV type 1-infected children.
Author	Cressey TR,Green H,Khoo S,Treluyer JM,Compagnucci A,Saidi Y,Lallemant M,Gibb DM,Burger DM,Paediatric European Network for Treatment of AIDS II Study Group.
Evidence	One child who was receiving nevirapine had the NNRTI resistance mutation K103N detected 14 days after stopping treatment with nevirapine, but this child had a viral load of 700 copies/mL at day 0 (<50 copies/mL at the screening visit), and the K103N resistance mutation could also be detected in virus isolated from a stored sample taken at day 0.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation