HIV Mutation Detail Information

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Mutation Information

Mutation Site	K103N
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	NNRTIs
Country	spain

Literature Information

PubMed PMID	17559687
Disease	HIV infection/AIDS
Published Year	2007
Journal	BMC infectious diseases
Title	Predictive factors of virological success to salvage regimens containing protease inhibitors in HIV-1 infected children.
Author	Larru B,de Mendoza C,Bellón JM,de José MI,Mellado MJ,Soriano V,Muñoz-Fernandez MA,Ramos JT
Evidence	At baseline, the median number of Nucleotide Analogue Mutations (NAMs) was 3.0 (1.5-4) and the median number of protease resistance mutations was 5.0 (2-6.5). M184V was found in 11 children (33%);3 of them (30.3%) were resistant to Abacavir and 1 of them (15.2%) was resistant to Tenofovir according to the virtual phenotype. At baseline, 42.4% of children have NNRTI mutations;30.3% have the K103N and 15.2% the Y181C.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation