Mutation Information
Mutation Site
|
K101P |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
NNRTIs |
Literature Information
PubMed PMID
|
32493197
|
Published Year
|
2020 |
Journal
|
Current HIV research |
Title
|
Application of Structure-based Methods to Analyze Resistance Mutations for Chemically Diverse Non-Nucleoside Reverse Transcriptase Inhibitors. |
Author
|
Tabassum T,Azeem SM,Muwonge AN,Frey KM |
Evidence
|
The DeltaS + DeltaA values for K101P suggest that this mutation confers intermediate/high-level resistance to MIV-150, but remains susceptible to doravirine.
|
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