|
Mutation Information
|
Mutation Site
|
K101E |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
lamivudine (LAM);tenofovir (TDF);efavirenz (EFV) |
|
Country
|
china |
Literature Information
|
PubMed PMID
|
33122923
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
Infection and drug resistance |
|
Title
|
Transmitted and Acquired HIV-1 Drug Resistance from a Family: A Case Study. |
|
Author
|
Yan L,Yu F,Zhang H,Zhao H,Wang L,Liang Z,Zhang X,Wu L,Liang H,Yang S,Tang Y,Zhang F |
|
Evidence
|
Mother also acquired K101E (41.03%), K103N (27.56%) and minor mutation of V106M (4.30%) after improperly discontinuing antiretroviral regimen of lamivudine (3TC), tenofovir (TDF) and efavirenz (EFV).
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HIV Mutation Detail Information