HIV Mutation Detail Information

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Mutation Information

Mutation Site	K101E
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	NNRTIs
Country	Botswana

Literature Information

PubMed PMID	33031315
Disease	HIV infection/AIDS
Published Year	2020
Journal	Medicine
Title	Differences in human immunodeficiency virus-1C viral load and drug resistance mutation between plasma and cerebrospinal fluid in patients with human immunodeficiency virus-associated cryptococcal meningitis in Botswana.
Author	Kelentse N,Moyo S,Mogwele M,Lechiile K,Moraka NO,Maruapula D,Seatla KK,Esele L,Molebatsi K,Leeme TB,Lawrence DS,Musonda R,Kasvosve I,Harrison TS,Jarvis JN,Gaseitsiwe S
Evidence	The third had K101E in plasma and V106 M in CSF.Our findings suggest that HIV-1 escape and DRM discordance may occur at lower rates in participants with advanced HIV-disease and CM compared to those with HIV associated neurocognitive impairment.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation