|
Mutation Information
|
Mutation Site
|
K101E |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
lamivudine (LAM);efavirenz (EFV) |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
32267205
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
Emerging microbes & infections |
|
Title
|
Efficacy and safety of lower dose tenofovir disoproxil fumarate and efavirenz versus standard dose in HIV-infected, antiretroviral-naive adults: a multicentre, randomized, noninferiority trial. |
|
Author
|
Chen J,Chen R,Shen Y,Wei H,Wang X,Zhang R,Hu Z,Xie R,Huang Q,Wang J,Liu L,Qi T,Wang Z,Song W,Tang Y,Sun J,Lu H |
|
Evidence
|
HIV genotyping resistance testing demonstrated HIV-associated mutations for 3TC and EFV resistance (M184V, K101E and G190S) in one case in the lower dose regimen group.
|
|
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HIV Mutation Detail Information