Mutation Information
Mutation Site
|
K101E |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Country
|
Caucasian;sub-Saharan Africa |
Literature Information
PubMed PMID
|
32259255
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2020 |
Journal
|
The Journal of antimicrobial chemotherapy |
Title
|
Characterization of viral rebounds on dual etravirine/raltegravir maintenance therapy (ANRS-163 ETRAL trial). |
Author
|
Soulie C,Assoumou L,Abdi B,Sayon S,Nguyen T,Valantin MA,Beniguel L,Ferre V,Alloui C,Montes B,Avettand-Fenoel V,Delaugerre C,Descamps D,Martinez E,Reynes J,Peytavin G,Costagliola D,Katlama C,Calvez V,Marcelin AG,ANRS-163 ETRAL study group. |
Evidence
|
Some RT variants became dominant at VF (K101E, 86.3%;Y181C, 100.0%;G190A, 100.0%) and others emerged in integrase (Y143C, 2.4%;Q148R, 6.2%;N155H, 18.8%).
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