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Mutation Information
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Mutation Site
|
K101E |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
|
Viral Reference
|
K03455.1
|
|
Country
|
France |
Literature Information
|
PubMed PMID
|
29856864
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2018 |
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Journal
|
PloS one |
|
Title
|
Evaluation of different analysis pipelines for the detection of HIV-1 minority resistant variants. |
|
Author
|
Perrier M,Désiré N,Storto A,Todesco E,Rodriguez C,Bertine M,Le Hingrat Q,Visseaux B,Calvez V,Descamps D,Marcelin AG,Charpentier C |
|
Evidence
|
In four other cases, MRVs were detected at frequencies greater than 2% by one of the software programs while not being detected by the other: (i) one case was corrected after manual review (V179D), (ii) one case exhibited a low coverage below 1,000 reads (K101E), (iii) one displayed a correct alignment by the two software programs (T69S), and (iv) one was located in a homopolymeric region (K65E) that generated misalignment with AVA .
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HIV Mutation Detail Information