HIV Mutation Detail Information

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Mutation Information
Mutation Site K101E
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Genotype/Subtype C
Relevant Drug NNRTIs
Country South Africa
Literature Information
PubMed PMID 22293461
Disease HIV infection/AIDS
Published Year 2012
Journal Antiviral therapy
Title Low rates of nucleoside reverse transcriptase inhibitor resistance in a well-monitored cohort in South Africa on antiretroviral therapy.
Author Wallis CL,Papathanasopolous MA,Fox M,Conradie F,Ive P,Orrell C,Zeinecker J,Sanne I,Wood R,McIntyre J,Stevens W,CIPRA-SA project 1 study team.
Evidence Of the five with resistance at enrollment, no NRTI resistance was observed, two had resistance to NNRTIs (K103N n=1; V106M, K103N n=1), two had protease resistance (M46I n=1, M46L n=1) and one had both protease and NNRTI resistance (M46V, K101E, G190A).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation