Mutation Information
Mutation Site
|
K101E |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
NNRTIs |
Literature Information
PubMed PMID
|
20102272
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2010 |
Journal
|
The Journal of infectious diseases |
Title
|
Low frequency nonnucleoside reverse-transcriptase inhibitor-resistant variants contribute to failure of efavirenz-containing regimens in treatment- experienced patients. |
Author
|
Halvas EK,Wiegand A,Boltz VF,Kearney M,Nissley D,Wantman M,Hammer SM,Palmer S,Vaida F,Coffin JM,Mellors JW |
Evidence
|
101E showed a trend toward clustering (bootstrap value 46) with failure sequences containing L100I/K101E/Y188L or L100I/K101E/G190A (figure 2E).
|
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