HBV Mutation Detail Information

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Mutation Information

Mutation Site	I86T
Mutation Type	Amino acid level
Gene/Protein/Region Type	S
Genotype/Subtype	D

Literature Information

PubMed PMID	11481624
Disease	Fulminant hepatitis B
Published Year	2001
Journal	Hepatology (Baltimore, Md.)
Title	A dominant hepatitis B virus population defective in virus secretion because of several S-gene mutations from a patient with fulminant hepatitis.
Author	Kalinina T,Riu A,Fischer L,Will H,Sterneck M
Evidence	In addition to the 7 common mutations of the mutant S-proteins, there are 3 substitutions (N40S, I86T, and Y134F)that were only present in 2 of the 3 variant genome sequences(Fig. 1)

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation