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Mutation Information
|
Mutation Site
|
I85V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PR |
|
Relevant Drug
|
PIs |
|
Country
|
Uganda |
Literature Information
|
PubMed PMID
|
32025714
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
The Journal of antimicrobial chemotherapy |
|
Title
|
Prevalence of viral load suppression, predictors of virological failure and patterns of HIV drug resistance after 12 and 48 months on first-line antiretroviral therapy: a national cross-sectional survey in Uganda. |
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Author
|
Ssemwanga D,Asio J,Watera C,Nannyonjo M,Nassolo F,Lunkuse S,Salazar-Gonzalez JF,Salazar MG,Sanyu G,Lutalo T,Kabuga U,Ssewanyana I,Namatovu F,Namayanja G,Namale A,Raizes E,Kaggwa M,Namuwenge N,Kirungi W,Katongole-Mbidde E,Kaleebu P,Uganda HIV Drug Resistance Technical Working Group. |
|
Evidence
|
One patient (1.1%;95% CI 0.14%-3.6%) had the I85V PI mutation, 23 (90.3%;95% CI 65.6%-97.9%) had NRTI mutations, 26 (94.1%;95% CI 74.3%-98.9%) had NNRTI mutations and 22 (89.5%;95% CI 64.7%-97.5%) had both NRTI and NNRTI mutations (Table 2).
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HIV Mutation Detail Information