|
Mutation Information
|
Mutation Site
|
I85L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
LMP1 |
|
Viral Reference
|
V01555.2
|
|
Country
|
Swiss |
Literature Information
|
PubMed PMID
|
22384168
|
|
Disease
|
B-cell lymphoma;
T-cell lymphoma;
Hodgkin lymphoma
|
|
Published Year
|
2012 |
|
Journal
|
PloS one |
|
Title
|
Genetic diversity of EBV-encoded LMP1 in the Swiss HIV Cohort Study and implication for NF-Κb activation. |
|
Author
|
Zuercher E,Butticaz C,Wyniger J,Martinez R,Battegay M,Boffi El Amari E,Dang T,Egger JF,Fehr J,Mueller-Garamvögyi E,Parini A,Schaefer SC,Schoeni-Affolter F,Thurnheer C,Tinguely M,Telenti A,Rothenberger S,Swiss HIV Cohort Study. |
|
Evidence
|
The comparison of the amino acid sequences of variants P1 and A2 within residues 1 to 118 shows two common polymorphisms: I85L and F106Y (Figure 1D), which were introduced individually in the B95-8 sequence to evaluate their influence.
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EBV Mutation Detail Information