HIV Mutation Detail Information

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Mutation Information

Mutation Site	I84V
Mutation Type	Amino acid level
Gene/Protein/Region Type	PR

Literature Information

PubMed PMID	33175558
Published Year	2020
Journal	Langmuir : the ACS journal of surfaces and colloids
Title	Multiple Molecular Dynamics Simulations of the Inhibitor GRL-02031 Complex with Wild Type and Mutant HIV-1 Protease Reveal the Binding and Drug-Resistance Mechanism.
Author	Wang R,Zheng Q
Evidence	For instance, compared with the WT PR, L90M and V82F/I84V mutations cause the flaps to be more open,(60,61) while M46I and I50L/A71V mutations cause the flaps to be more closed.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation