Mutation Information
Mutation Site
|
I84V |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
PR |
Literature Information
PubMed PMID
|
32053707
|
Published Year
|
2020 |
Journal
|
PLoS pathogens |
Title
|
HIV protease cleaves the antiviral m6A reader protein YTHDF3 in the viral particle. |
Author
|
Jurczyszak D,Zhang W,Terry SN,Kehrer T,Bermúdez González MC,McGregor E,Mulder LCF,Eckwahl MJ,Pan T,Simon V |
Evidence
|
Briefly, HIV-MDR1 encodes two major protease inhibitor resistance associated mutations (PR I84V and L90M) while HIV-MDR2 only has one (PR L90M).
|
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