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Mutation Information
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Mutation Site
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I84V |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
PR |
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Relevant Drug
|
PIs |
|
Country
|
USA |
Literature Information
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PubMed PMID
|
30148406
|
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Disease
|
HIV infection/AIDS
|
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Published Year
|
2018 |
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Journal
|
AIDS research and human retroviruses |
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Title
|
Prevalence of Darunavir Resistance in the United States from 2010 to 2017. |
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Author
|
Brown K,Stewart L,Whitcomb JM,Yang D,Nettles RE,Lathouwers E |
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Evidence
|
Mutations included in the analysis were based on the IAS-USA protease mutation list. The 11 darunavir RAMs were V11I, V32I, L33F, I47V, I50V, I54L/M, T74P, L76V, I84V, and L89V. The 23 primary PI RAMs were D30N, V32I, M46I/L, I47A/V, G48V, I50 L/V, I54 L/M, Q58E, T74P, L76V, V82A/F/L/S/T, N83D, I84V, N88S, and L90M.
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HIV Mutation Detail Information