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Mutation Information
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Mutation Site
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I82M |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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PR |
Literature Information
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PubMed PMID
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33503916
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Published Year
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2021 |
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Journal
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Molecules (Basel, Switzerland) |
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Title
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Structural Impacts of Drug-Resistance Mutations Appearing in HIV-2 Protease. |
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Author
|
Laville P,Petitjean M,Regad L |
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Evidence
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The I82M mutant was particular because it had no MCS atoms, revealing that the I82M mutation induced few structural changes in PR2 structure. In contrast, the K7R mutant was the mutant with the most MCS atoms (147 MCS located in 53 different residues as illustrated in Figure 4.
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HIV Mutation Detail Information