HBV Mutation Detail Information

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Mutation Information

Mutation Site	I68N
Mutation Type	Amino acid level
Gene/Protein/Region Type	S
Genotype/Subtype	adw2

Literature Information

PubMed PMID	10385663
Disease	HBV infection
Published Year	1999
Journal	Hepatology (Baltimore, Md.)
Title	Mutational pattern of hepatitis B virus on sequential therapy with famciclovir and lamivudine in patients with hepatitis B virus reinfection occurring under HBIg immunoglobulin after liver transplantation.
Author	Tillmann HL,Trautwein C,Bock T,Böker KH,Jäckel E,Glowienka M,Oldhafer K,Bruns I,Gauthier J,Condreay LD,Raab HR,Manns MP
Evidence	One patient (NR21) selected a I68N and P120Tcorresponding to mutations N424K and T476N within theHBV-DNA polymerase, 2 patients (R03, PR11) selected aE164D corresponding to a V521L mutation within the HBV-DNA polymerase, 1 (R02) selected a Q120P mutationon FCV, and another 1 (R04) selected a W172Stop mutationof the HBsAg corresponding to a A529T mutation within the HBV-DNA polymerase

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation